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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight reduction in addition to a reduced-calorie diet and physical activity.

Using two separate drugs to shed pounds can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight loss and the people that go through it you need to err on the side of caution and allow the FDA do its job and demand some investigation be done in order that the public is aware of the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies are in business to earn money and that they would say almost anything to keep people on his or her medications.

Researchers found that participants investing in this drug to get a year, dropped a few pounds within a month and have kept the extra weight off during the entire 56 weeks in the study. Contrave is really a combination from the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of multiple active ingredient, that might make them far better and safer.

Combo-pilling could be the newest fad or better yet the newest to come under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills has become popular could be the fact that by right now there aren't long term prescription diet pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures certainly are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug could also raise blood pressure levels and heart rate, and must not be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure and heart rate and must 't be used in patients with uncontrolled high blood pressure, along with by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients which has a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients for the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.

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